Journal of Acquired Immune Deficiency Syndromes (JAIDS) Online Submission and Review System

Instructions for Authors (this page) Copyright Transfer (.doc) Reprint Ordering Permissions Requests ePRints Reprints Mandatory Authorship Checklist (.doc)

SCOPE
The Journal of Acquired Immune Deficiency Syndromes is a peer-reviewed, multidisciplinary journal directed to an audience of physicians and researchers. The journal publishes original articles in the form of rapid communications, original research reports, short reviews, brief reports, and letters to the editor. JAIDS generally does not publish case reports.

MANUSCRIPT SUBMISSION
A submitted manuscript must be an original contribution not previously published (except as an abstract or preliminary report), must not be under consideration for publication elsewhere, and, if accepted, must not be published elsewhere in similar form, in any language, without the consent of Lippincott Williams & Wilkins. Each person listed as an author is expected to have participated in the study to a significant extent. Although the editors and referees make every effort to ensure the validity of published manuscripts, the final responsibility rests with the authors, not with the journal, its editors, or the publisher.

All submissions will be rigorously peer-reviewed by members of the Editorial Board, and possibly by other specially qualified individuals as well. In the interests of rapid reviewing of contributions, only one of the Editors-in-Chief will, in general, make the final determination as to the acceptability of a submission, after collecting the referee's comments. Contributors may recommend specific names of reviewers from the Editorial Board, as well as other individuals they deem especially well qualified. However, the Editors-in-Chief will not be bound to follow such suggestions.

In general, the instructions for preparation of manuscripts should follow the International Committee of Medical Journal Editors (ICMJE) Uniform Requirements for Manuscripts Submitted to Biomedical Journals. In case of questions, please feel free to contact the Editorial Office of any one of the Editors-in-Chief.

Authors must submit their manuscripts to the relevant section through the Web-based tracking system: Basic Science (http://jaids-basicscience.edmgr.com), Clinical Science (http://jaids-clinical.edmgr.com), or Epidemiology (http://jaids-epidemiology.edmgr.com). The site contains instructions and advice on how to use the system, guidance on the creation/scanning and saving of electronic art, and supporting documentation. In addition to allowing authors to submit manuscripts on the Web, the site allows authors to follow the progression of their manuscript through the peer review process. Authors should not send hard copies of the manuscript to the editorial office. They may, however, send to the editorial office any artwork, letters, or files that cannot be submitted electronically. Address all inquiries regarding manuscripts not yet accepted or published to the Journal's editorial office. The editorial office will acknowledge receipt of your manuscript via e-mail.

Editorial Office Addresses
Basic Science Articles
David D. Ho, MD
The Aaron Diamond AIDS
Research Center
455 First Avenue
New York, NY 10016
(212) 448-5171
Fax: (212) 725-1126
dgottwal@adarc.org

Clinical Articles
Paul A. Volberding, MD
San Francisco VA Medical Center
Building 16
4150 Clement Street
VAMC 111V
San Francisco, CA 94121
(415) 379-5546
Fax: (415) 379-5547
jaids@chi.ucsf.edu

Epidemiology Articles
William A. Blattner, MD
Institute of Human Virology
725 W. Lombard Street, S419
Baltimore, MD 21201
(410) 706-1287
Fax: (410) 706-1944
lbarrett@ihv.umaryland.edu

Authorship
An author is considered to be someone who has made substantive contributions to a published study. Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content. More specifically, authorship credit requires a) substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data; b) drafting the paper or revising it critically for important intellectual content; and c) final approval of the version to be published. Contributors must meet conditions for a, b, and c—all 3—to be eligible for authorship. All persons listed as authors must meet the 3 criteria above, and all persons who meet the above criteria must be listed as authors. Please note that acquisition of funding, collection of data, or general supervision of a research group, alone, does not justify authorship.

All papers must include a completed Mandatory Authorship Checklist at the time of submission.
For large, multicenter group studies, individuals who accept direct responsibility for the manuscript must be identified. Those individuals will be required to complete the JAIDS Copyright Transfer form.

Contributors who do not meet the criteria for authorship should be listed in the acknowledgments section. Persons providing technical help, writing assistance, or a department chair providing general support are examples of persons who should not be included as authors, but who should be listed in the Acknowledgments section.

Conflict of Interest Declaration and Mandatory Checklist
Authors must disclose all financial and personal relationships that might bias their work. The Mandatory Authorship Checklist must be completed for each submission, and it is on this form (or in an attachment) that conflicts of interest must be detailed. Conflicts that are determined to be substantial may be printed in the journal in a footnote on the first page of the article.

Studies funded by an agency with a proprietary or financial interest in the outcome must include a statement with information about the sponsor(s) involvement. Authors involved in such a study must state whether they had full access to all of the data and take full responsibility for the accuracy of the data analysis.

Copyright
All authors must complete and sign a copy of the journal's Copyright Transfer form and submit it when submitting the original manuscript online.

Compliance with NIH and Other Research Funding Agency Accessibility Requirements
A number of research funding agencies now require or request authors to submit the post-print (the article after peer review and acceptance but not the final published article) to a repository that is accessible online by all without charge. As a service to our authors, LWW will identify to the National Library of Medicine (NLM) articles that require deposit and will transmit the post-print of an article based on research funded in whole or in part by the National Institutes of Health, Wellcome Trust, Howard Hughes Medical Institute, or other funding agencies to PubMed Central. The revised Copyright Transfer Agreement provides the mechanism.
Patient Anonymity and Informed Consent
It is the author's responsibility to ensure that a patient's anonymity be carefully protected and to verify that any experimental investigation with human subjects reported in the manuscript was performed with informed consent and following all the guidelines for experimental investigation with human subjects required by the institution(s) with which all the authors are affiliated. Authors should mask patients’ eyes and remove patients’ names from figures unless they obtain written consent from the patients and submit written consent with the manuscript.

Protection of Human Subjects and Animals in Research
When reporting experiments involving human subjects, authors should indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000.
For research involving animals, authors should indicate whether the procedures followed were in accordance with the standards set forth in the Guide for the Care and Use of Laboratory Animals (published by the National Academy of Science, National Academy Press, Washington, D.C.).

Permissions
Authors must submit written permission from the copyright owner (usually the publisher) to use direct quotations, tables, or illustrations that have appeared in copyrighted form elsewhere, along with complete details about the source. Any permissions fees that might be required by the copyright owner are the responsibility of the authors requesting use of the borrowed material, not the responsibility of Lippincott Williams & Wilkins.

PREPARATION OF MANUSCRIPT
Manuscripts that do not adhere to the following instructions will be returned to the corresponding author for technical revision before undergoing peer review.

Online Submission
Manuscript files must be uploaded into the Editorial Manager online interface. Most word-processing file formats are acceptable. Editorial Manager will then create PDF files of the authors' submission, and the author must view and approve the files before they will be submitted to the editorial office. Please be sure that the manuscript file contains complete text for your submission (title page and abstract), as this is the file that will be downloaded by the reviewers and publisher. Please see the sections below for instructions regarding Figure and Table files.
Once the paper has been accepted for publication, and final versions of the manuscript, figures, and table files have been uploaded to the Editorial Manager interface, PDF files will not be used for typesetting. This is important to note for Table and Figure files, which may lose formatting when converted to PDF, but will remain intact in their original file format.

Title Page
A title page must be included in the manuscript file. Include on the title page: a) complete manuscript title; b) authors' full names, academic degrees, and affiliations; c) name and address for correspondence, including fax number, telephone number, and e-mail address; d) address for reprints if different from that of corresponding author; e) meetings at which parts of the data were presented (including title of conference, city, and date); f) sources of support; and g) a running head of no more than 40 characters.

The title page must also include disclosure of funding received for this work from any of the following organizations: National Institutes of Health (NIH); Wellcome Trust; Howard Hughes Medical Institute (HHMI); and other(s).

Abstract and Key Words
The abstract should be structured and limited to 200 words. It must be factual and comprehensive. Limit the use of abbreviations and acronyms, and avoid general statements (eg, "the significance of the results is discussed"). List 3 to 6 key words or phrases.

Text
Organize the manuscript file into sections with appropriate section headings. The sequence should be as follows: title page, abstract/key word page, introduction, methods, results, discussions, acknowledgments, references, tables, figures and figure captions.

Authors should type, whenever possible, all mathematical and chemical symbols, equations, and formulas, and identify all unusual symbols the first time they are used. Define abbreviations at first mention in text and in each table and figure. If a brand name is cited, supply the manufacturer's name and address (city and state/country).

Abbreviations
For a list of standard abbreviations, consult the Council of Biology Editors Style Guide (available from the Council of Science Editors, 9650 Rockville Pike, Bethesda, MD 20814) or other standard sources. Write out the full term for each abbreviation at its first use unless it is a standard unit of measure.

References
The authors are responsible for the accuracy of the references. Key the references (double-spaced) at the end of the manuscript. (If using End Note, set the style output to JAMA.) Cite references in text in order of appearance. Cite unpublished data, such as papers submitted but not yet accepted for publication, or personal communications, in parentheses in the text. If there are more than 3 authors, list only the first 3 authors and then use et al. Refer to the List of Journals Indexed in Index Medicus for abbreviations of journal names. Sample references are given below:

Journal Article

Book Chapter

Entire Book

Software

Online Journals

Database

World Wide Web

Paper Presented at a Conference


Figures
Cite figures consecutively in the text, and number them in the order in which they are discussed. We encourage authors to submit their figures through Editorial Manager, but if this is not possible, authors may send hard copies of the figures to the editorial office for scanning. On the hard copies, be sure to write the first author's last name, the figure number and figure part (1A, 1B, 1C), and an arrow to indicate the top edge of the figure on a label pasted to the back of each figure. Submit all artwork in camera-ready form; illustrations should be glossy prints or high-quality, laser-printed illustrations. Photocopies are unacceptable. Authors who submit manuscripts through Editorial Manager may submit figures as separate electronic files. High-quality hard copies may be requested once the manuscript has been accepted for publication. Lettering should be large enough that it will remain legible after figure reduction; typewritten or unprofessional lettering is unacceptable. Figure parts (A, B, C) may be left unlabeled (but clearly marked on back) for professional placement by the journal's printer.

Figure Legends
Legends must be submitted for all figures. They should be included in the manuscript file, should be brief and specific, and should appear on a separate manuscript page after the references. Use scale markers in the image for electron micrographs, and indicate the type of stain used.

Color Figures
The journal accepts for publication color figures that will enhance an article. Authors who submit color figures will receive an estimate of the cost for color reproduction. If they decide not to pay for color reproduction, they can request that the figures be converted to black and white at no charge.

Digital Figures
Electronic art should be created/scanned and saved and submitted as either a TIFF (tagged image file format), an EPS (encapsulated postscript) file, or a PPT (Power Point) file. Line art must have a resolution of at least 1200 dpi (dots per inch), and electronic photographs—radiographs, CT scans, and so on—and scanned images must have a resolution of at least 300 dpi. If fonts are used in the artwork, they must be converted to paths or outlines or they must be embedded in the files. Color images must be created/scanned and submitted as CMYK files. Files should be submitted electronically through the Editorial Manager interface. Please note that artwork generated from office suite programs such as Corel Draw and MS Word and artwork downloaded from the Internet (JPEG or GIFF files) cannot be used.

Supplemental Digital Content
Authors may submit supplemental digital content to enhance their article's text and to be considered for online-only posting. Supplemental digital content may include the following types of content: text documents, graphs, tables, figures, graphics, illustrations, audio, and video. Cite all supplemental digital content consecutively in the text. Citations should include the type of material submitted, should be clearly labeled as "Supplemental Digital Content," should include a sequential number, and should provide a brief description of the supplemental content. Provide a legend of supplemental digital content at the end of the text. List each legend in the order in which the material is cited in the text. The legends must be numbered to match the citations from the text. Include a title and a brief summary of the content. For audio and video files, also include the author name, videographer, participants, length (minutes), and size (MB). Authors should mask patients' eyes and remove patients' names from supplemental digital content unless they obtain written consent from the patients and submit written consent with the manuscript. Copyright and Permission forms for article content including supplemental digital content must be completed at the time of submission.

Supplemental Digital Content Size & File Type Requirements
To ensure a quality experience for those viewing supplemental digital content, it is suggested that authors submit supplemental digital files no larger than 10 MB each. Documents, graphs, and tables may be presented in any format. Figures, graphics, and illustrations should be submitted with the following file extensions: .tif, .eps, .ppt, .jpg, .pdf, .gif. Audio files should be submitted with the following file extensions: .mp3, .wma. Video files should be submitted with the following file extensions: .wmv, .mov, .qt, .mpg, .mpeg, .mp4. Video files should also be formatted with a 320 X 240 pixel minimum screen size. For more information, please review LWW's requirements for submitting supplemental digital content: http://links.lww.com/A142

Tables
Create tables using the table creating and editing feature of your word-processing software (eg, Word, Word-Perfect). Do not use Excel or comparable spreadsheet programs. Group all tables at the end of the manuscript, or supply them together in a separate file. Cite tables consecutively in the text, and number them in that order. Key each on a separate sheet, and include the table title, appropriate column heads, and explanatory legends (including definitions of any abbreviations used). Do not embed tables within the body of the manuscript. They should be self-explanatory and should supplement, rather than duplicate, the material in the text.

Style
Pattern manuscript style after the American Medical Association Manual of Style (9^th edition). Stedman's Medical Dictionary (28^th edition) and Merriam-Webster's Collegiate Dictionary (11^th edition) should be used as standard references. Refer to drugs and therapeutic agents by their accepted generic or chemical names, and do not abbreviate them. Use code numbers only when a generic name is not yet available. In that case, supply the chemical name and a figure giving the chemical structure of the drug. Capitalize the trade names of drugs and place them in parentheses after the generic names. To comply with trademark law, include the name and location (city and state in USA; city and country outside USA) of the manufacturer of any drug, supply, or equipment mentioned in the manuscript. Use the metric system to express units of measure and degrees Celsius to express temperatures, and use SI units rather than conventional units.

Obligation to Register Clinical Trials
JAIDS has adopted the standards of the International Committee of Medical Journal Editors with regard to the registration of clinical trials. As a condition of consideration for publication, data from research projects “prospectively assigning human subjects to intervention or concurrent comparison or control groups to study the cause-and-effect relationship between a medical intervention and a health outcome” must be registered in a public trials registry. The Protocol Registration System (http://prsinfo.clinicaltrials.gov/) offered through the U.S. National Institutes of Health is one such registry.

GenBank Accession Numbers
When manuscripts include or describe original nucleotide or amino acid sequence data, the sequence must be submitted to the GenBank/EMBL/DDBJ sequence database and an accession number obtained from them. This accession number must be returned to the journal, where it will be placed after the Key Words on the title page in the printed article. URLs for the 3 members of the International Nucleotide Sequence Database Collaboration (GenBank/EMBL/DDBJ) are as follows (respectively): http://www.ncbi.nlm.nih.gov/BankIt/, http://www.ebi.ac.uk/embl/, http://www.ddbj.nig.ac.jp/.

ARTICLE TYPES

Original Articles
The above guidelines apply to the original article format. There is no length limitation for original articles, but authors are encouraged to be succinct, as papers that are overlong do not fare well in peer review.

Rapid Communications
Articles accepted as Rapid Communications will normally be published within 8 weeks of acceptance. When submitting a paper for consideration as a Rapid Communication, please adhere to the following guidelines:

• Submit your paper to Editorial Manager and designate the article type as "Rapid Communication." Please indicate to the Editor in a cover letter file why the paper merits special attention.
• If figures cannot be submitted to Editorial Manager, authors must send them by overnight express.
• The paper should not exceed 6 printed pages (approximately 24 double-spaced typewritten manuscript pages, including illustrations, tables, and references).
• The paper should include an abstract, key words, methods, results, discussion, and reference sections.
• The title page should include the corresponding author's telephone and fax numbers and e-mail address.
• Authors will receive proofs of their article for review by e-mail and will be expected to return corrections by fax within 24 hours of receipt. Changes received after this deadline will not be accepted.

Papers that are not accepted as Rapid Communications may be considered as full-length articles.

Critical Reviews
Papers reviewing the literature on a particularly timely and interesting topic will be considered for publication in JAIDS. Authors are encouraged to keep review articles to less than 24 double-spaced manuscript pages, including references, tables, and figure legends. In general, review articles written as work-for-hire by industry employees will not be considered for publication. All funding, writing assistance, and other relationships to possibly conflicted sources must be fully disclosed at the time of submission.

Brief Reports
Brief Reports are short versions of clinical studies. They represent observations that are preliminary, speak for themselves, or offer new insight into a recognized condition. Submissions should not exceed 10 double-spaced manuscript pages, including references and table. Manuscripts that are too long for this category will be shortened at the editorial office or returned to the author for shortening.

Letters to the Editor
Letters to the Editor can provide additional comment on an article published in JAIDS, or can be a very concise report on study findings. Letters should be no more than 3 typeset pages (6 manuscript pages double-spaced, including references and either 1 figure or 1 table [but no abstract]).

Page Proofs and Corrections
Portable document format (PDF) files of the copyedited, typeset pages and support documents (eg, reprint order form) will be sent to the corresponding author via e-mail. Complete instructions will be provided with the e-mail for downloading and printing the files and for faxing the corrected pages to the publisher. It is the author's responsibility to ensure that there are no errors in the proofs. Changes that have been made to conform to journal style should be allowed to stand if they do not alter the authors’ meaning. Only critical changes improving the accuracy of the content will be made. Changes that are stylistic or are a reworking of previously accepted material will not be allowed. The publisher reserves the right to deny any changes that do not affect the accuracy of the content. Authors may be charged for alterations to the proofs beyond those required to correct errors or to answer queries. Proofs must be checked carefully and corrections faxed within 24 to 48 hours of receipt, as requested in the cover letter accompanying the page proofs.

Reprints
Reprint orders should be submitted to the Reprints Department (1-800-341-2258 or reprints@LWW.com). Payment for reprints or a purchase order number must accompany your order form. Orders without these cannot be fulfilled.

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